유럽 배양육(Cultured Meat) 양산을 위한 10톤급 대형 배양기 프로젝트

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10-Ton Large-Scale Bioreactor Project for Cultured Meat Production in Europe

Project Overview

European cultivated meat company B was moving forward with the construction of a 10-ton / 10,000 L large-scale production plant based on successful lab-scale results.

However, due to limited ceiling height in the facility, a top-entry agitator could not be installed. At the same time, the process required both a low-shear environment, essential for cultivated meat formation, and an extremely hygienic design meeting EHEDG-level standards.

To achieve a customized hygienic mixing solution, Company B ultimately selected SEDNA ENG’s SRF / HSS magnetic agitator models.

Challenges

1. Factory Ceiling Height Limitation

Although the tank capacity was as large as 10 tons, there was no available space to install a motor on the top due to the facility’s height limitations. A powerful drive system was required to control large-volume fluid while utilizing the lower space of the tank.

2. Shear Control for Tissue Formation

Cultured meat requires cells to aggregate and form tissue, making it extremely sensitive to shear stress. A large Ø1000 blade design was essential to uniformly mix heavy culture medium while operating at low RPM.

3. Hygienic Design to Prevent Cross-Contamination

As cultivated meat is classified as a food product, cross-contamination caused by residues can be critical. A drainable structure with no liquid pooling and complete protection against culture medium penetration into component gaps were required.

SEDNA Solution

1. Bottom-Mount & Custom Large Impeller

To overcome ceiling height limitations, SEDNA ENG applied a bottom-mounted magnetic mixer, placing the motor and gearbox at the bottom of the tank. A custom Ø1000 large impeller was also designed to generate sufficient fluid flow even at low RPM.

2. EHEDG-Grade Hygienic Design

To minimize shear stress and improve cleanability, the impeller blades and dish-shaped head were finished with super polishing for a smooth hygienic surface. Special elastomer sealing was also applied to prevent liquid ingress into internal components, ensuring hygienic performance in line with EHEDG guidelines.

3. Fully Drainable Zero-Pooling Structure

The lower part of the impeller was precisely machined to match the tank bottom geometry, creating a zero-pooling structure with no residual liquid after drainage

PROBLEM

SOLUTION

01 Fully Resolved Space Limitations

Successfully achieved 10-ton scale-up with a bottom-mounted drive system, without expanding the facility space.

02 Optimized Cell Viability and Tissue Formation

Created an optimal environment for cultured meat tissue formation through low-shear design and meticulous surface finishing.

03 Completed Global Logistics and Installation

Safely delivered and supported the installation of large-scale precision equipment manufactured in Korea, proving SEDNA ENG’s global project execution capability.

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